去氧肾上腺素杂质 26
2-Amino-3'-hydroxy-acetophenone HCl
CAS: 14665-75-9
Molecular Formula: C8H9NO2.ClH
去氧肾上腺素杂质 26 - Names and Identifiers
| Name | 2-Amino-3'-hydroxy-acetophenone HCl |
| Synonyms | Phenylephrine Impurity 26 2-AMino-3'-hydroxy-acetophenone HCl 2-Amino-3'-hydroxy-acetophenone HCl 2-amino-1-(3-hydroxy-phenyl)-ethanone 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE 2-Amino-1-(3-hydroxyphenyl)ethanone Hydrochloride |
| CAS | 14665-75-9 |
去氧肾上腺素杂质 26 - Physico-chemical Properties
| Molecular Formula | C8H9NO2.ClH |
| Molar Mass | 187.625 |
| Melting Point | 221–222°C |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | Solid |
| Color | Pale Beige to Brown |
| Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
去氧肾上腺素杂质 26 - Introduction
2-Amino-3 '-hydroxy-acetophenone HCl is an organic compound with the chemical formula C8H10ClNO2 and the structural formula NH2-C6H4-CH(OH)-C(O)CH3 · HCl. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: White crystalline solid.
-Solubility: Soluble in water and some organic solvents.
-Melting point: About 176-178 ° C.
-Storage conditions: should be stored in a cool and dry place, away from fire and oxidizing agents.
Use:
-Drug synthesis: 2-Amino-3 '-hydroxy-acetophenone HCl is a commonly used intermediate that can be used to synthesize a variety of drugs, such as painkillers and anti-inflammatory drugs.
Method:
2-Amino-3 '-hydroxy-acetophenone HCl synthesis method is relatively simple, a commonly used preparation method is as follows:
1. Acetophenone oxide was obtained by reacting acetophenone with silver nitrite.
2. The acetophenone oxide was reacted with ammonia to obtain 2-amino -3 '-hydroxyacetophenone.
3.2-Amino-3 '-hydroxyacetophenone reacts with hydrochloric acid to give 2-Amino-3'-hydroxy-acetophenone HCl.
Safety Information:
- 2-Amino-3 '-hydroxy-acetophenone HCl is irritating, avoid skin contact and inhalation, and pay attention to protective measures, such as wearing gloves and goggles.
-Good laboratory safety practices should be followed during operation, and attention should be paid to the cleaning of appliances and proper disposal of chemical waste.
-In case of inadvertent contact or ingestion of the substance, seek immediate medical help and take the chemical label or container to the hospital.
Nature:
-Appearance: White crystalline solid.
-Solubility: Soluble in water and some organic solvents.
-Melting point: About 176-178 ° C.
-Storage conditions: should be stored in a cool and dry place, away from fire and oxidizing agents.
Use:
-Drug synthesis: 2-Amino-3 '-hydroxy-acetophenone HCl is a commonly used intermediate that can be used to synthesize a variety of drugs, such as painkillers and anti-inflammatory drugs.
Method:
2-Amino-3 '-hydroxy-acetophenone HCl synthesis method is relatively simple, a commonly used preparation method is as follows:
1. Acetophenone oxide was obtained by reacting acetophenone with silver nitrite.
2. The acetophenone oxide was reacted with ammonia to obtain 2-amino -3 '-hydroxyacetophenone.
3.2-Amino-3 '-hydroxyacetophenone reacts with hydrochloric acid to give 2-Amino-3'-hydroxy-acetophenone HCl.
Safety Information:
- 2-Amino-3 '-hydroxy-acetophenone HCl is irritating, avoid skin contact and inhalation, and pay attention to protective measures, such as wearing gloves and goggles.
-Good laboratory safety practices should be followed during operation, and attention should be paid to the cleaning of appliances and proper disposal of chemical waste.
-In case of inadvertent contact or ingestion of the substance, seek immediate medical help and take the chemical label or container to the hospital.
Last Update：2024-04-09 15:17:52
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Product Name: 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Visit Supplier Webpage Request for quotation
CAS: 14665-75-9
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CAS: 14665-75-9
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